DYMO reports the following information about this problem on their website:

"We are aware of a problem with the tape compartment of the DYMO LabelWriter 450 Duo .This is related to the recent Windows 10 software update (KB5015807).DYMO would like to apologize for the inconvenience caused and provide this step-by-step guide with the most common solutions. If this does not solve the problem, do not hesitate to contact us directly."

Below you can download the document  download (PDF) that DYMO has prepared to help you solve your problem. If you experience any problems, please contact DYMO Helpdesk.

LW450 DUO probleem na update Windows 10